Mediglobe collaborates with clinics in Northern Cyprus for Egg and Embryo Donation Treatment

In vitro fertilization (IVF) is a widely used assisted reproductive technology (ART) that helps individuals and couples conceive when natural pregnancy is challenging. When combined with preimplantation genetic testing (PGT), IVF can significantly improve the chances of a healthy pregnancy by screening embryos for genetic abnormalities before implantation. Therefore In vitro fertilisation (IVF) has become a beacon of hope for couples facing infertility, and Mediglobe recommends affordable, high-quality IVF treatments. Moreover, Mediglobe is in cooperation with IVF clinics in Northern Cyprus that work to European and American standards and have accreditation.

What is IVF with PGT?

In Vitro Fertilization (IVF):

IVF involves fertilizing an egg with sperm outside the body in a laboratory. The resulting embryos are cultured for a few days before being transferred into the uterus.

Preimplantation Genetic Testing (PGT):

PGT is an advanced genetic screening technique used during IVF to analyse embryos for:

• Chromosomal abnormalities (PGT-A, formerly PGS)
• Single-gene disorders (PGT-M)
• Structural rearrangements (PGT-SR)

Only genetically normal embryos are selected for transfer, increasing the likelihood of a successful pregnancy and reducing the risk of genetic diseases.

How does IVF with PGT Process? Step-by-Step

Ovarian Stimulation & Egg Retrieval:

• Hormonal injections stimulate the ovaries to produce multiple eggs.
• Eggs are retrieved via a minor surgical procedure under sedation.

Fertilization (ICSI or Conventional IVF):

• Sperm fertilizes the eggs in a lab (often using intracytoplasmic sperm injection (ICSI) for precision).

Embryo Culture (3-6 Days):

• Embryos grow in a controlled environment until they reach the blastocyst stage (Day 5-6).

Embryo Biopsy for PGT:

• A few cells are carefully removed from each embryo’s outer layer (trophectoderm).
• The biopsied cells are sent for genetic testing while embryos are frozen.

Genetic Analysis & Embryo Selection:

• PGT identifies embryos with the correct number of chromosomes (euploid) and screens for specific genetic disorders.
• Only the healthiest embryos are chosen for transfer.

Frozen Embryo Transfer (FET):

• The selected embryo is thawed and transferred into the uterus in a subsequent cycle.
• Pregnancy is confirmed via blood test (~10-14 days later).

Mediglobe collaborates modern IVF clinics with Northern Cyprus, experienced IVF specialists, and recommend personalised treatment plans.

Who is a candidate for IVF with PGT?

PGT is particularly beneficial for:

Couples with a history of genetic disorders (e.g., cystic fibrosis, sickle cell anaemia).
Women over 35 (higher risk of chromosomally abnormal embryos).
Couples with recurrent miscarriages (often due to chromosomal issues).
Those with previous IVF failures (to improve implantation rates).
Carriers of chromosomal translocations (to prevent unbalanced embryos).

What are the Benefits of IVF with PGT?

✔ Higher Pregnancy Success Rates: Reduces miscarriage risk by selecting viable embryos.
✔ Lower Risk of Genetic Disorders: Screens for conditions like Down syndrome, Tay-Sachs, etc.
✔ Fewer IVF Cycles Needed: Avoids transferring embryos that would not implant.
✔ Family Balancing (Optional): Some use PGT for gender selection when permitted.

What are the Potential Risks of IVF with PGT?

No Guarantee of Pregnancy: Even genetically normal embryos may not implant.
Embryo Damage Risk (Low): Biopsy carries a slight risk of harming the embryo.
Mosaicism Challenges: Some embryos have mixed normal/abnormal cells, complicating results.

What are the success rates of IVF with PGT?

PGT can improve IVF success rates by 10-20%, especially in women over 35. Reduces miscarriage risk from ~25% to <10% in some cases. Mediglobe cooperates with IVF clinics in Northern Cyprus with high success rates.

Conclusion

Finally, IVF with PGT is a powerful tool for increasing the chances of a healthy pregnancy, especially for those at risk of genetic disorders or recurrent IVF failures. While it involves additional costs and steps, the benefits of higher implantation rates, reduced miscarriage risk, and healthier babies make it a valuable option for many.

As a result, if you’re considering IVF with PGT, consult Mediglobe to determine if it’s right for you. Mediglobe offers medical tourism packages that include airport transfers, accommodation, translation services, and aftercare. Mediglobe recommends world-class treatment, high success rates at lower costs (70% lower than Western countries), no waiting lists, English-speaking doctors & international standards, fewer bureaucratic hurdles than the EU, combining IVF Treatment with a peaceful, scenic recovery.

This article is for informational purposes and is not a substitute for professional medical advice, diagnosis, or treatment recommendation.